I've lost friends because they moved or we moved. But that type loss is just physical, and connections can still be there through letters, phone calls, email, and/or visits.
The losses that require many layers of bubble wrap are the permanent-in-this-lifetime ones. Two dear friends suffered from and fought cancer until cancer won. I miss them and always will until such time as we're together again.
As I write this, my best friend and adopted sister is undergoing open heart surgery. We didn't know her heart struggled with multiple blockages, serious ones of 95 - 99 percent. Her doctor put her in the hospital because of an asthma flare that couldn't be controlled. She didn't improve after four days. Instead she had two heart "episodes" Sunday evening and night. Monday her doctor had her transported by ambulance to the Heart Hospital in Oklahoma City. This morning she is in surgery,which will last five to six hours.
I pray that God wraps her in bubble wrap and keeps her safe.